Adsorption characterization of various modified β-cyclodextrins onto TEMPO-oxidized cellulose nanofibril membranes and cryogels

TEMPO-Oxidized cellulose nanofibrils (toCNF), in the form of highly entangled network such as membrane or cryogels, have proven to be interest for various applications, including drug release purification by pollutant adsorption. β-Cyclodextrins (β-CDs) ability inclusion complexes with large amount hydrophobic molecules, and are considered a promising way bring new functionalities these materials, reducing burst effect improving adsorption properties. The study β-CDs onto toCNF is then crucial design toCNF/β-CDs but very complex due chemical proximity between compounds. In this study, we develop cryogels containing types derivatives physical Different protocols analyzing interactions compounds, Isothermal Titration Calorimetry (ITC), Quartz-Crystal Microbalance dissipation monitoring (QCM-d) Phenolphthalein-based protocol (PhP protocol) been performed. Adsorption β-CD was at two different temperatures ITC. QCM-d measurements allowed measuring toCNF, higher measured modified β-CDs, estimated binding capacity ranging from 13.4 47.6 μmol/g toCNF. PhP us monitor released aqueous environment, highlighting lower results were consistent capacity. This quantification key optimizing materials.